Research & Development

Technology Awards

Sysmex Receives the “Invention Prize” in 2022 National Commendation for Invention

Sysmex Corporation has received the “Invention Prize” in 2022 National Commendation for Invention sponsored by Japan Institute of Invention and Innovation for “invention of rapid accurate method for measuring platelets using dye for platelets”.  This is the third year in a row we receive an award in the National Commendation for Invention.
 
The National Commendation for Invention started in 1919 for the purpose of contributing to the development and advancement of science and technology in Japan, and commends inventions, devices, and designs that had great achievements, or those expected to have big achievements in the future due to their excellence.
 
 Award Details 
  Title of the award: Invention Prize in 2022 National Commendation for Invention
  Title of the award-winning invention: Invention of rapid and accurate method for measuring platelets using dye for platelets (JP Patent No. 4659122)
  Winners: Keiko Moriyama, Yusuke Mori, Hiroki Takeshita, Yuhgi Suzuki
 
Description of the invention: This invention relates to a method for measuring platelets, which is important indicator for determining the necessity of platelet transfusion and the amount of platelet transfusion.
Conventionally, as a method for measuring platelets using a blood cell counter, a method of classifying and counting the platelets depending on the size of red blood cell or platelet by using a direct current detection method has been known. While this method provides a rapid and accurate measurement of the platelets in most samples, it was difficult to accurately count the platelets in a sample which has a low platelet count and thus needs a decision of platelet transfusion because of the influence of other particles of similar size.
According to this invention, platelets in a blood sample are stained with Nile blue and the forward scattered light and the side fluorescence of individual platelet are measured according to the principle of flow cytometry. As platelets can be differentiated from other particles, it is possible to count platelets accurately and also rapidly (1 minute).
The invention enables to measure platelet counts which is an important indicator for determining the necessity of platelet transfusion and the amount of platelet transfusion, therefore assisting optimization of dose of a platelet preparation that is precious. In addition, the invention contributes to reduce the risk of adverse reactions associated with platelet transfusion.
Result of classification by this invention

 

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