Cell Measurement Technologies
We are working on technology development which is establishing analysis of the number of and type of cells in the blood and intracellular information.
Cell Measurement Technologies : Flow cytometry technology（FCM technology）
Blood counters use specialized reagents (hemolytic and staining agents) for determining types of blood cells. Hemolytic agents include surface-acting agents, which are mixed with peripheral blood in the reaction chamber.
Surface-acting agents act to hemolyze red blood cells and increase the cell membrane permeability of white blood cells. Cells’ external forms and internal structures change, and morphological differences are generated depending on the cell characteristics of individual white blood cells. In addition, specialized staining agents are used for the specific fluorescent staining of the nucleic acid within cells and intracellular organelles. Differences in blood cell fluorescence are generated depending on the nucleic acid and the type and quantity of intracellular organelles.
A scattergram is produced based on the detected fluorescence and scattered light, and an analysis algorithm is used to identify blood cell types. This allows for precise detection of the target cell.
