Environment

Reduction in Environmental Burden through Business Activities

Involvement with Biodiversity

Sysmex considers it essential to address “natural capital,” including water, forests, and soil, alongside climate change countermeasures, and pursues an integrated approach to these challenges. In 2025, based on the recommendations of the TNFD, we identified freshwater and soil as natural capital most relevant to our business activities in terms of dependencies and impacts. Considering our resource usage and production scale, we selected three sites in Japan for an environmental impact assessment. We evaluated the effects on nearby areas and assessed Sysmex's actions and their effectiveness in using resources properly. The assessment found no significant environmental impacts on the surrounding areas. In the future, we plan to gradually increase the number of sites we assess.

Impact Assessment of Three Sites in Japan

Site	Main dependencies and influences		Impact on the community
Technopark	Fresh water	Use of groundwater	No adverse effects on the surrounding area, such as land subsidence, have been confirmed due to its use. Establish a continuous monitoring system for proper management of water resources and reduction of water consumption, such as reporting to Kobe City once every two months.
Ono factory	Fresh water	Use and discharge of water resources	Compared to the amount of water distributed by the municipality, the impact on the community is limited. The annual usage and emissions tend to decrease.
Ono factory	Soil	Use of plastic containers	Compared to the total production of plastic materials in Japan, the amount used is extremely small, and the impact on the environment is limited. Further reduction in consumption is expected through horizontal recycling and substitution of environmentally friendly materials.
i-Square	Soil	Use and disposal of metals (Iron)	Compared to the total amount of iron produced in Japan, the impact on the environment is limited as a very small amount of iron production. With a recycling rate of 96% and the conversion of waste into valuable materials, we are making effective use of resources at a high level.

Click here for disclosures based on the TCFD and TNFD recommendations

Initiatives to Reduce Greenhouse Gas Emissions

Efforts to Reduce Greenhouse Gas Emissions at Business Sites

Sysmex is working on energy conservation through the introduction of equipment such as highly efficient air conditioning systems, LED lighting, and motion sensors, as well as demand-control systems for measuring and monitoring the amount of electricity needed to reduce direct and indirect greenhouse gas emissions from our business sites.
In fiscal 2023, all electricity used by major domestic facilities, including reagent production factories and R&D centers, was switched to renewable energy sources. Sysmex RA, one of the Group’s key factories, received Net Zero Energy Building (ZEB¹) certification under the Building-Housing Energy-efficiency Labeling System (BELS²) for its new facility, which is scheduled to begin operations in April 2025.
Sysmex Europe’s reagent production factory has introduced ice thermal storage air conditioning systems³, in addition to having solar panels installed, covering approximately 35% of energy requirements for reagent production. In addition, Sysmex business locations in EMEA⁴ and the Americas have been increasing their usage of electricity derived from renewable energy.
Sysmex America has formed a cross-departmental Green Team to promote environmental activities with a view to obtaining LEED certification⁵ for its head office. It has also installed charging ports for electric vehicles, improved LED lighting, and installed solar panels, continuing to undertake various initiatives to acquire certification.

1 ZEB (Net Zero Energy Building): A building that aims to achieve a net zero annual volume of primary energy consumed and generated by installing highly efficient facilities systems to realize significant energy savings (energy conservation) while still maintaining the quality of the indoor environment and introducing renewable energy (energy creation)
2 BELS (Building-Housing Energy-efficiency Labeling System): A system to label energy saving efforts of buildings in accordance with the Act on the Improvement of Energy Consumption Performance of Buildings (Buildings Energy Efficiency Act)
3 Thermal energy storage technology using ice
4 Europe, the Middle East, and Africa
5 LEED evaluates the environmental performance of a building from the viewpoints of environmental burden reduction and the health of its users. Evaluation items include the efficiency of water usage, optimization of energy use, conservation of resource materials, and building air quality.

New Factory (Sysmex RA)

Major Initiatives at Each Business Site

Initiative	Company	Details
Increase the efficiency of equipment and facilities	Sysmex Corporation	Switch to highly efficient air conditioning and LED lighting Increase productivity through a production optimization initiative
	Sysmex CNA	Use LEDs for all lighting
	Sysmex America	Use LEDs for all lighting
	Sysmex Europe	Use LEDs for lighting in major reagent-filling rooms Introduce motion sensors
	Sysmex Asia Pacific	Use LEDs for lighting in factories and warehouses Introduce a control panel that puts the equipment to sleep to save energy when the air compressor is not in use
	Sysmex India	Use LEDs for lighting in factories
	Jinan Sysmex	Use natural gas boilers (switching from oil boilers) Switch from gas boilers to air-source heat pumps for indoor heating during the winter and to heat raw water
	Sysmex Wuxi	Save energy with restrictions to air conditioning temperature settings
Introduce renewable energy	Sysmex Corporation	Install solar panels Save energy by bringing in natural light (i-Square) and use electricity from renewable energy sources
	Sysmex America Sysmex Reagents America	Use electricity from renewable energy sources Switch to 100% carbon-neutral natural gas
	Sysmex Europe	Install solar panels Use electricity from renewable energy sources (all electricity)
	Sysmex UK	Install solar panels
	Jinan Sysmex	Install solar panels
Raise employee awareness	Sysmex Europe	Provide incentives for using trains for business trips, establish an in-house website for car sharing, and provide bikes for commuting
	Sysmex Malaysia	Provide incentives to employees who use hybrid vehicles for commuting
	Sysmex India	Ensure that all personal vehicles used by employees to commute are PUC certified*
	Sysmex Brazil	Switch to biofuel for company vehicles

Acronym for “Pollution Under Control,” which certifies that vehicle emissions are below pollution regulation standards.

Decreasing CO₂ Emissions from Company Vehicles

In order to control fuel consumption and reduce CO₂ emissions for the approximately 400 company vehicles in Japan, Sysmex Corporation has installed telematics services in the form of drive recorders in each vehicle to enable visualization of driving quality, such as each car’s eco-drive status and compliance with laws. It also conducts eco-driving training for all employees to improve the environmental awareness of each driver. With these activities being evaluated highly, Sysmex received a certificate of excellence in the fiscal 2024 Eco-Driving Activity Contest sponsored by the Foundation for Promoting Personal Mobility and Ecological Transportation. It has also promoted the replacement of its company vehicles with those that have greater fuel efficiency. By the end of fiscal 2024, approximately 60% of all our vehicles were replaced with hybrid or fuel-efficient vehicles.
We are also promoting the introduction of environmentally friendly vehicles and fuels across its global operations. Sysmex Brazil uses biofuels derived from sugarcane for its company cars and is expanding the use of electric vehicles for deliveries from its own warehouses to customers. Sysmex UK has eliminated diesel vehicles and replaced all company vehicles with hybrid models.

Using Water Resources Efficiently

Reducing Water Consumption

Sysmex uses water as a raw material in reagent production. Both tap water and groundwater are used. Recognizing that reducing water use is an important issue, Sysmex has set targets for decreasing water use in our Eco-Vision 2033, and it is making efforts to improve the efficiency of water use at reagent production sites.
At the Ono Factory, a reagent production factory, Sysmex has successfully reduced the number of line cleanings by increasing the number of consecutive production runs for the same product, after thoroughly confirming there would be no impact on product quality. In addition, by reviewing production processes, we have developed technology to recover and commercialize the reagents without discarding remaining liquid in the piping. These initiatives have contributed to reducing water use and lowering environmental impact from waste liquid.

Major Initiatives at Each Business Office

Company	Initiatives
Sysmex Corporation	Reduce water consumption by improving production efficiency at diagnostic reagent production factories At Technopark, draw water from wells for use in greenery and toilets, with usage amounts monitored appropriately
Sysmex Asia Pacific	Improve its ultrapure water plant to recycle RO water (purified water), utilizing times when the plant is not in operation Reduce water consumption by monitoring efficiency of purified water production equipment Reduce consumption of water used to wash production facilities after reagent production
Sysmex India	Recycle water generated in the production process for use as irrigation water Install at the new factory a zero liquid discharge system* that aims to eliminate water discharge outside the factory site
Sysmex Brazil	Recycle water generated in the production process for use as domestic water Modify cleaning system for purified water production equipment that operates 24 hours a day to operate only on weekdays
Sysmex Wuxi	Set a target for reducing water consumption, assign an officer dedicated to environmental, health, and safety issues, and conduct periodic environmental, health, and safety inspections Review and optimize processes and cycles for water use in production to enhance efficiency and reduce consumption

A system that purifies and reuses wastewater from factories through multiple treatment methods, thereby eliminating wastewater discharge outside the factory premises.

New Production Base in India

Wastewater Management and Processing

Sysmex prioritizes the protection of water quality. We have created our own emission standards that we use to manage the wastewater from development centers and factories that use chemical substances, ensuring that waterways and groundwater are not affected.

Major Initiatives at Each Business Office

Company	Initiative
Sysmex Corporation	Introduce a system to set off an alarm in the event that BOD (Biochemical Oxygen Demand) standards are exceeded at the Ono Factory, a diagnostic reagent production plant, preventing waste fluid containing organic matter from spilling out
Sysmex RA	Introduce waste fluid processing equipment, making infectious waste fluid harmless by heat sterilization, and discharge the harmless fluid directly into the sewage system
Sysmex America	Introduce a wastewater processing system to remove boron-containing substances from waste fluid generated during reagent production
Sysmex Asia Pacific	Introduce a wastewater processing system to purify waste fluid generated during reagent production before discharging it to the sewage system
Jinan Sysmex	Commission third-party institutions to appropriately process recyclable waste, such as waste drums and waste paper generated during the production process

Managing and Recycling Waste

Reducing Waste and Promoting a Stable Recycling Rate

Sysmex carries out initiatives to reduce waste and increase recycling rates. At our research and development base, Technopark, we introduced polystyrene foam melting machines and large shredders for confidential paper in fiscal 2023. With this equipment, we can convert all used polystyrene foam generated from the office into recycled plastic materials and sell them as valuable resources. We also process the shredded wastepaper from large shredders to be reused as toilet paper. By doing this, we can significantly reduce the volume of waste.
In addition, we began selling as valuable resources our own and metal scrap from unneeded freezers and refrigerators, resulting in approximately 56 tons of recycled resources in fiscal 2024.
In its domestic reagent production factories, Sysmex promotes environmental initiatives in collaboration with its business partners and has successfully reduced the waste of packing materials for delivery by reusing cardboard, reviewing excessive packaging, and changing the practice of over-packaging.
At our domestic instrument production factories, i-Square and Kakogawa Factory, we conducted trial separation of mixed plastic waste and sold approximately 10 tons as valuable resources in fiscal 2024. Furthermore, at Kakogawa Factory, food waste from its in-house canteen is reduced using a specialized garbage disposal system that converts food waste into organic fertilizer for farmers. The factory purchases agricultural produce grown by the farmers who use this fertilizer, contributing to the realization of a circular economy.

Regarding the reduction of waste through the recycling of packing materials and parts, etc., please see “Environmental Consideration in Product Transportation, Sales, and Services.”

Promoting Digital Data

Sysmex works to reduce its use of paper by utilizing personal computers, tablets, and smartphones to send and receive data. These efforts have reduced paper use and waste. Our manufacturing facilities are also working to switch to electronic production records and manuals, promoting our paperless initiative.

Major Initiatives at Each Business Office

Company	Initiative
Sysmex America	Switching the reagent waste processing method from landfill to energy-from-waste treatment (During the three years from 2023 to 2025, 50 to 100 tons of waste is expected to be recycled.)
Sysmex Brasil	Reuse polystyrene foam and refrigerants used in import packaging in collaboration with partner companies
Sysmex Medica	Switched 100% of copier paper from plain paper to environmentally friendly paper
Sysmex Asia Pacific	Replace aluminum foil used for weighing drums with reusable materials Recycle containers made from chemical ingredients that were previously discarded
Sysmex Malaysia	Recycle or donate to charities cardboard boxes and plastic materials
Sysmex Jinan	Replace sludge filter press equipment and conduct QC activities to lower the water content of the sludge and reduce emissions of harmful substances

Status of Sustainability Targets

Managing Harmful Substances

Managing Chemical Substances

Sysmex uses chemical substances in its R&D and manufacturing processes. In addition to preventing losses or leaks, we strive to manage chemical substances appropriately to prevent damage to the health of our employees working onsite.

Chemical Substance Management of Products

Managing and Processing Harmful Substances

As a precaution against the danger of infection by biological substances, we strictly control the locations in which such substances are stored and used. These substances are carefully segregated from general waste for proper disposal. For other harmful substances, we work to prevent aerial drift, dispersion, and groundwater permeation through countermeasures that address both facilities and management methods. In these ways, we endeavor to keep emissions below standard statutory levels.

Managing and Processing Atmospheric Emissions

In response to the Fluorocarbons Emission Control Law, each Group company in Japan established a response manual, identifying and appropriately using fluorocarbon-containing instruments owned or managed by it, conducting inspections, and monitoring calculated amount of leaked fluorocarbons.

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