Research & Development
Academic Report
2025
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Paper Publication
- Artificial intelligence-driven label-free detection of chronic myeloid leukemia cells using ghost cytometry
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Conference Presentation
- Prediction of Perioperative ischemic events in neuroendovascular treatments by APAL system
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Conference Presentation
- Comparative study of four platelet function tests calculated through two techniques
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Conference Presentation
- Inflammatory phenotypes of severe asthma from sputum and plasma proteomic profiles
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Conference Presentation
- Diagnostic Potential of Q-flag (RBC Agglutination?) and Q-flag (Fragments?) in Beta Thalassemia: A Comparative Analysis with Nutritional Anaemias
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Conference Presentation
- Impact of Folate Deficiency on Leukocyte and Platelet Parameters: A Comparative Analysis with Iron and Vitamin B12 Deficiencies
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Conference Presentation
- HER2 protein localization in super-resolution and anti-HER2 therapy response in breast cancer
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Paper Publication
- Low atypical lymphocyte score as a predictor of non-severe dengue
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Conference Presentation
- Development of a highly specific p-tau205 assay using a fully automated immunoassay system
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Paper Publication
- Effects of storage time and temperature on coagulation factor and natural anticoagulant activities in healthy individuals
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Paper Publication
- Importance of EQA/PT for the detection of genetic variants in comprehensive cancer genome testing
2024
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Paper Publication
- Rapid Surface-Enhanced Raman Scattering Imaging and Deep Learning for Highly Sensitive Discrimination of Amino Acids and Peptides
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Conference Presentation
- Plasma Aβ measured using a fully automated immunoassay platform predicts brain Aβ accumulation with high robustness
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Conference Presentation
- Detection of antigen-specific activated T cells using imaging flow cytometry
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Conference Presentation
- The snapshot of Sysmex, Bio-Diagnostic Reagent Technology Center
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Conference Presentation
- Development of evaluation method for HDL function (Cholesterol uptake capacity) using the fully automated immunoassay system HISCL™-series.
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Paper Publication
- Performance evaluation and user experience of BT-50 transportation unit with automated and scheduled quality control measurements
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Conference Presentation
- Elevated levels of soluble form of immune checkpoint in patients with aggressive adult T-cell leukemia-lymphoma
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Paper Publication
- Clinical and analytical validation of an 82-gene comprehensive genome-profiling panel for identifying and interpreting variants responsible for inherited retinal dystrophies
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Conference Presentation
- Possibility of the Sysmex XN series hematopoietic progenitor cells (HPC) as a substitute for CD34-positive cell counts in allogeneic peripheral blood stem cell harvest from G-CSF mobilized related donor.
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Paper Publication
- Mitral regurgitation is associated with similar loss of von Willebrand factor large multimers, but lower frequency of anemia compared with aortic stenos
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Conference Presentation
- Electrolyte and metabolic abnormalities and dengue severity in adults
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Conference Presentation
- The snapshot of Sysmex, Bio-Diagnostic Reagent Technology Center: Together for a better healthcare journey
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Conference Presentation
- Construction of a reliable CTC detection method and validity evaluation of CTC markers in colorectal cancer
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Conference Presentation
- Development of a fully automated immunoassay system of serum pembrolizumab to forecast therapeutic effectiveness
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Conference Presentation
- Method for detection of antigen-specific T cell using imaging flow cytometry
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Conference Presentation
- T-B doublet formation represents early signs of antigen-specific T cell activation
2023
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Conference Presentation
- PERFORMANCE EVALUATION OF AUTOMATED HEMATOLOGY ANALYZER XN-31 PROTOTYPE FOR MALARIA PARASITES DETECTION AT MAHIDOL UNIVERSITY'S OUTPATIENT CLINIC IN BANGKOK, THAILAND
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Conference Presentation
- Feasibility study: Monitoring parasitemia in the course of malaria patient treatment with automated hematology analyzer XN-31
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Conference Presentation
- Evaluation of pre-analytical sample handling procedure for plasma Aβ measurement using a fully automated immunoassay system
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Conference Presentation
- Single-EV analysis based on sequential digital bioassay
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Conference Presentation
- Single-EV Analysis based on Sequential Digital Bioassays
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Paper Publication
- Novel Approach for Obtaining Variable Domain of New Antigen Receptor with Different Physicochemical Properties from Japanese Topeshark (Hemitriakis japanica)
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Paper Publication
- Seamless and non-destructive monitoring of extracellular microRNAs during cardiac differentiation from human pluripotent stem cells
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Conference Presentation
- New Innovations in Clinical Testing Pioneered by Robots
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Paper Publication
- Arginine cluster introduction on framework region in anti-lysozyme antibody improved association rate constant by changing conformational diversity of CDR loops
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Paper Publication
- DEVELOPMENT AND PRACTICAL USE OF A SEX-LIMITED HYBRID “MR” WITH THE NAKED PUPA TRAIT FOR THE RECOMBINANT PROTEIN PRODUCTION IN THE SILKWORM, BOMBYX MORI
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Conference Presentation
- Correlations of p-tau217, p-tau181 and tau levels between CSF and plasma that are measured by fully automated immunoassay platform
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Conference Presentation
- Evaluation of acute period bacterial infection by XN-V software of automated hematology analyzer for animal in rats
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Conference Presentation
- Detection of Mulberry Bodies using Imaging Flow Cytometry
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Paper Publication
- A Fluorescence Cross-Correlation-Spectroscopy-Based Immunoassay for Rapid, Selective, and Accurate Protein Sizing in Human Plasma, Applied to the von Willebrand Factor
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Conference Presentation
- Development of high-sensitivity and compact Immunoassay measurement system utilizing microfluidic reaction technology
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Conference Presentation
- Development of plasma p-tau231 assay on a fully automated immunoassay system.
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Conference Presentation
- Effects of combined pre-analytical sample handling variables on plasma β-amyloid level measured using a fully automated immunoassay system.
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Paper Publication
- Imaging flow cytometry-based multiplex FISH for three IGH translocations in multiple myeloma
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Paper Publication
- Fully automated immunoassay for cholesterol uptake capacity to assess high-density lipoprotein function and cardiovascular disease risk
2022
- 【Conference presentation】Plasma Aβ assay measured using a fully automated immunoassay platform predicts the amyloid PET status
- 【Conference presentation】Three group classification of participants based on fully automated plasma β-amyloid measurements to achieve high positive and negative predictive values.
- 【Conference presentation】Effects of pre-analytical parameters on plasma β-amyloid level.
- 【Conference presentation】Age dependency of plasma β-amyloid measured by fully automated and highly specific immunoassays in a Japanese cohort study (SESSA).
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Conference Presentation
- EVALUATION OF THE MALARIA DETECTION PERFORMANCE OF XN-31 PROTOTYPE, THE AUTOMATED HEMATOLOGY ANALYZER, CONDUCTED AT OUTPATIENT CLINIC IN MAHIDOL UNIVERSITY IN THAILAND
- 【Conference presentation】Compact Immunoassay System Using Microfluidic Technology
- 【Publication of a paper】Potential application of the haematology analyser XN-31 prototype for field malaria surveillance in Kenya
- 【Publication of a paper】Detection of histidine-rich protein 2- and/or 3-deleted Plasmodium falciparum using the automated hematology analyzer XN-31: A proof-of-concept study
- 【Conference presentation】 Development of fully automated plasma immunoassay using by HISCL™ series for classification of neurological disorders
- 【Conference presentation】Highly specific plasma β-amyloid assays on the fully automated platform predict brain β-amyloid pathology determined by a Centiloid threshold of amyloid PET
- 【Publication of a paper】Development and clinical usefulness of OncoBEAM™ RAS CRC Kit
- 【Publication of a paper】Clinical performance testing of the automated haematology analyzer XN-31 prototype using whole blood samples from patients with imported malaria in Japan
- 【Publication of a paper】Fully automated and highly specific plasma β-amyloid immunoassays predict β-amyloid status defined by amyloid positron emission tomography with high accuracy
- 【Conference presentation】Development of biomarkers to predict response of immune checkpoint inhibitors in lung cancer
- 【Publication of a paper】Enzymatic measurement of short-chain fatty acids and application in periodontal disease diagnosis
- 【Publication of a paper】Mirror-image streptavidin with specific binding to L-biotin, the unnatural enantiomer
- 【Publication of a paper】Highly sensitive and non-disruptive detection of residual undifferentiated cells by measuring miRNAs in culture supernatant
- 【Conference presentation】Attitude of leukocytes activation in dengue patients using hematology analyzer parameters
- 【Conference presentation】 Immunophenotyped-suspension-multiplex FISH by imaging flow cytometry for the simultaneous diagnosis of three pivotal IGH translocations in multiple myeloma
- 【Conference presentation】Mirror-image streptavidin with specific binding to non-natural L-biotin
- 【Conference presentation】Introduction of inter-domain SS bond into Fab domain improve antibody stability without affinity change
- 【Conference presentation】Verification of the performance of ghost cytometry in discriminating unlabeled leukemia cells, and analysis of their morphology and function.
- 【Conference presentation】Imaging flow cytometry-based multiplex FISH for three IGH translocations in multiple myeloma
- 【Conference presentation】Examination of atypical cell detection by measurement information of BF mode of Automated Hematology Analyzer XR-Series
- 【Conference presentation】Development of calibration-free All-Solid-State ion sensor chip with inorganic insertion material paste and inorganic solid electrolyte
- 【Conference presentation】Development of a High-throughput Microfluidic Sequential-sorting System for the Enrichment of Rare Cells
- Fully Automated Plasma Beta-Amyloid Immunoassays Predict Amyloid Pathology Defined by Amyloid PET
- Plasma Biomarkers for Classification of AD Pathology by a Fully Automated Immunoassay System (HISCL™ series)
- The Evaluation of Plasma Aβ1-40 and Aβ1-42 Immunoassays on the Fully Automated Immunoassay Platform (HISCL™ series)
2020
- Sysmex Presents Academic Report with a View to Creating a Simple Method of Diagnosing Alzheimer’s Disease Using Blood
- Sysmex Presents Academic Report Related to the Clinical Utility of RAS Gene Mutation Testing for Colorectal Cancer Using Liquid Biopsy Details of Report on Clinical Utility of OncoBEAM™ RAS CRC Kit presented at the American Society of Clinical Oncology Gastrointestinal Cancers Symposium 2020 (ASCO-GI 2020)