[Conference presentation] Presenting the 18th Clinical Trials on Alzheimer’s Disease conference (CTAD)

Sysmex Corporation will present the latest data on the development of blood-based biomarkers for Alzheimer's Disease at 18th Clinical Trials on Alzheimer’s Disease conference (CTAD) annual meeting to be held from December 1^st to 4^th, 2025 in San Diego, USA.

[Poster presentation]

Session	Subject	Presenter (Affiliation)
02. CLINICAL TRIALS: RESULT P092^*1	Analytical and clinical validation of the APOE genotyping PCR test in patients from the Phase III Clarity AD trial Decembe 1^st (PST)	Kozue Matsuda (SYSMEX)
07. CLINICAL TRIALS: BIOMARKERS INCLUDING PLASMA P227	Development of MTBR-tau Fragment Assay Using a Fully Automated Immunoassay System Decembe 3^rd (PST)	Shun Murakami (SYSMEX)
07. CLINICAL TRIALS: BIOMARKERS INCLUDING PLASMA P226^*2	Performance of plasma pTau217/Aβ42 ratio and pTau217 to predict Aβ pathology status defined by CSF testing in SPIN cohort Decembe 3^rd (PST)	Yuko Mori (Sysmex R&D Center Europe)

Session

Subject

Presenter
(Affiliation)

02. CLINICAL TRIALS:
RESULT
P092^*1

Analytical and clinical validation of the APOE genotyping PCR test in patients
from the Phase III Clarity AD trial

Decembe 1^st (PST)

Kozue Matsuda
(SYSMEX)

07. CLINICAL TRIALS:
BIOMARKERS
INCLUDING PLASMA
P227

Development of MTBR-tau Fragment Assay Using a Fully Automated
Immunoassay System

Decembe 3^rd (PST)

Shun Murakami
(SYSMEX)

07. CLINICAL TRIALS:
BIOMARKERS
INCLUDING PLASMA
P226^*2

Performance of plasma pTau217/Aβ42 ratio and pTau217 to predict
Aβ pathology status defined by CSF testing in SPIN cohort

Decembe 3^rd (PST)

Yuko Mori
(Sysmex R&D Center Europe)

[Poster Presentation by Prof. Charlotte Teunissen, Amsterdam UMC]

Session

Subject

07. CLINICAL TRIALS:
BIOMARKERS
INCLUDING PLASMA
P197^*3

High diagnostic performance of the random-access HISCL-5000 pTau217, Aβ42 and Aβ40 plasma assays
for detecting amyloid pathology across the Alzheimer’s disease clinical continuum.

Decembe 3^rd (PST)

[Poster Presentation from the Tokyo Metropolitan Institute for Geriatrics and Gerontology]

Session

Subject

07. CLINICAL TRIALS:
BIOMARKERS
INCLUDING PLASMA
P228^*4

Combination of Plasma Aβ42/40 and p-tau217 Measured Using Fully Automated Immunoassay System
Accurately Predicts Amyloid Pathology Determined by Amyloid PET

Decembe 3^rd (PST)

Terminology
*1 Co-presentation with Eisai Co., Ltd.
*2 Co-presentation with Hospital de la Santa Creu i Sant Pau, Spain
*3 Co-presentation with Amsterdam UMC
*4 Co-presentation with Tokyo Metropolitan Institute for Geriatrics and Gerontology

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