Research & Development
Technology Awards
| Title of the award: | Best Student Presentation Award (Oral Presentation) |
| Theme: | In Vivo Pharmacokinetics and Therapeutic Efficacy of Silicon Phthalocyanine Derivatives for Near-Infrared Photoimmunotherapy |
| Recipient: | Daiki Hara |
| Date of the award: | April 15, 2026 |
| Award details : | Near-infrared photoimmunotherapy is a novel treatment that selectively destroys cancer cells by accumulating an antibody drug conjugated with a photosensitizer in tumors and irradiating them with near-infrared light. In this study, we developed a therapeutic agent using a newly synthesized silicon phthalocyanine compound. Evaluation using a tumor-bearing mouse model showed that this agent exhibits higher tumor accumulation than conventional ones. In addition, nonspecific accumulation in normal organs such as the liver was suppressed, suggesting fewer side effects and the potential to achieve more effective near-infrared photoimmunotherapy. |
| Note: | This research was conducted by the researcher during his enrollment in a doctoral program for working professionals at Kansai Medical University. |