Sysmex Journal International

2018Vol.28 No.1


Performance Comparison of Two Sysmex Hematology Analyzers: the XN-550 and the XS-1000i


Qian-Yun ZHANG*, Jill CRIST*, Tiffany IVERS*

*1 Department of Pathology, University of New Mexico & TriCore Reference Laboratories
*2 Sysmex America, Inc.


Since 2011, Sysmex has been offering the XN-Series of hematology analyzers to support the needs of large clinical laboratories. With the global introduction of the XN-L Series in 2015, similar functionality, operability, and clinical parameters as the XN-Series are now available in a compact, automated, hematology analyzer well-suited for the small to medium-sized lab; for acute care settings; or for use in emerging markets where a larger analyzer may neither be cost-effective nor practical. The XN-L Series is also suitable as a backup analyzer where an XN-Series analyzer is already installed because they share the same user interface, reagents, and control solutions along with the accuracy and linearity compared with the XN-Series that has already been characterized.

The purpose of this study was to demonstrate that the analytical performance of The Automated Hematology Analyzer XN-550 (XN-550; Sysmex Corporation, Kobe, Japan), one of the XN-L Series analyzers, is comparable to the existing The Automated Hematology Analyzer XS-1000i (XS-1000i; Sysmex Corporation, Kobe, Japan) desktop analyzer, and to provide additional data demonstrating the precision and linearity of several parameters of the XN-L Series. This study was performed to evaluate the analytical performance of this instrument for the US market.