Sysmex Journal International

2017Vol.27 No.2


Identifying Poor Antiplatelet Drug Response and its Risks Early on


Sysmex Europe GmbH


Platelets are important cells for repairing endothelial lesions, initiating thrombus formation after vascular damage and modulating wound healing. They are also important in the formation of blood clots and so help to reduce the flow of blood through the circulatory system. Early analysis of in vivo platelet reactivity is important for detecting developing thrombotic events. For most of these patients, these analyses also serve as a forecast of future complications and help to evaluate the efficacy of antiplatelet medication.

Patients with acute coronary syndromes often have high immature platelet counts that the body produces to compensate for platelet loss caused by platelet aggregation due to atherosclerosis. Immature platelets have been found to play an important role in risk assessment and therapy monitoring of coronary artery diseases. The immature platelet count(IPF#)is a new diagnostic parameter and the IPF# value specifically reflects the absolute number of newly produced platelets in peripheral blood.


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