Performance Evaluation of the XN-550 Automated Hematology Analyzer Body Fluid Mode — Considerations for Operational Conditions for Cell Counting with Cerebrospinal and Synovial Fluids

• Performance Evaluation of the XN-550 Automated Hematology Analyzer Body Fluid Mode — Considerations for Operational Conditions for Cell Counting with Cerebrospinal and Synovial Fluids

AUTHOR(S)

Masami TANAKA, Ken-ichi SHUKUYA, Yoshifumi MORITA, Yuko KAGEYAMA,
Shigeo OKUBO, Tatsuo SHIMOSAWA and Yutaka YATOMI

Department of Clinical Laboratory, The University of Tokyo Hospital

SUMMARY

The performance of the body fluid mode on the Automated Hematology Analyzer XN-550 (XN-550; Sysmex Corporation, Kobe, Japan) was evaluated using cerebrospinal and synovial fluid samples. Correlations with the chamber counting method of cerebrospinal fluid were generally good for white blood cell, mononuclear cell, and polymorphonuclear cell counts (correlation coefficients: r = >0.952). However, drainage samples containing degenerative cells deviated from the chamber counting method. Correlations with the Automated Hematology Analyzer XN-9000 (XN-9000; Sysmex Corporation, Kobe, Japan) were good for white blood cell, mononuclear cell, and polymorphonuclear cell counts (correlation coefficients: r = >0.979). Correlations with the chamber counting method of synovial fluid were good for white blood cell, mononuclear cell, and polymorphonuclear cell counts (correlation coefficients: r = >0.911). The body fluid mode of XN-550 may become useful for tests on off-duty time by setting operational conditions.

KEY WORDS

Cerebrospinal Fluid, Synovial Fluid, Automated Hematology Analyzer, XN-550, White Blood Cell Count

NOTE(S)

This article is translated and republished from the Sysmex Journal Web Vol. 17 No. 2, 2016.