Comparison of the Sysmex XE-2100 to the SE-9500+RAM-1, Automated Hematology Analyzer

• Comparison of the Sysmex XE-2100 to the SE-9500+RAM-1, Automated Hematology Analyzer

AUTHOR(S)

Nina Gamperling and Cathy Trester

Sysmex Corporation of America, Gilmer Road, 6699 Wildlife Way, Long Grove, IL 60047-9596, USA.

SUMMARY

The Sysmex XE-2100 automated hematology analyzer was evaluated at a Sysmex Hematology Research Center. Results from 230 patient samples were compared to the Sysmex SE-9500+RAM-1. The XE-2100 showed excellent correlation with the results to the SE-9500+RAM-1 for the following parameters: white blood cell (WBC), neutrophil (Neut) %, lymphocyte (Lymph) %, monocyte (Mono) %, eosinophil (Eo) %, basophil (Baso) %, red blood cell (RBC), hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume(MCV), mean corpuscular hemoglobin (HCH), mean corpuscular hemoglobin concentration (MCHC), RBC distribution widthcoefficient of variation (RDW-CV), RBC distribution width-standard deviation (RDW-SD), reticulocyte (RET) % and #, immature reticulocyte fraction (IRF), platelet (PLT), mean platelet volume (MPV). It can be concluded that the overall performance of the XE-2100 compares favorably to the SE-9500+RAM-1. The XE-2100 is a fully automated hematology analyzer with simultaneous analysis of 32 parameters (26 reportable in the USA) including the NRBC and IRF parameters. The XE-2100 uses several methodologies from previous Sysmex instrumentation, along with a newly developed optical detection unit for the following parameters: WBC, WBC 5-part differential, NRBC count, reticulocyte analysis and optical platelet counting. The XE-2100 can process approximately 150 samples per hour, has various discrete analysis capabilities for cost-effective testing, and uses the Windows NT system for easy operation.

KEY WORDS

Automated Hematology Analyzer, XE-2100, Comparison, SE-9500+RAM-1

Received 2 April, 2002; Accepted 12 April, 2002