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  The current invention resolves these problems through a combination of optimum reagent composites, conditions and dyes, allowing the measurement of the urine as sampled. The new reagent consequently enables automatic classification and quantification of formed elements (red blood cells, white blood cells, bacteria, casts and epithelial cells) in approximately one minute. As a result, this invention has markedly enhanced the urinalysis efficiency and precision. The new reagent is used in fully automated urine cell analyzers such as the UF-100 series and the UF-1000i , resulting in the world's first practical application of automated quantitative analysis of formed elements in urine through the use of flow cytometry.
  Five related associations, including the Japanese Urological Association and the Japanese Society of Nephrology, and a study group of the Ministry of Health, Labour and Welfare, have drawn up hematuria diagnosis guidelines. These guidelines indicate the importance of determining the red blood cell count in the measurement of hematuria and list flow cytometry as one method for counting the number of blood cells present in urine.
  In these ways, this invention represents a major contribution to improving the efficiency and quality of medical care and the standardization of tests. 
  Going forward, Sysmex will continue to promote research and development that contributes to breakthroughs in healthcare and improvements in science and technology. 
 

[Schematic]

Detection and classification of formed elements through a combination of an automated urinary cell analyzer and the new reagent: illustration of fraction (1)

Detection and classification of formed elements: illustration of fraction (2) (Channel for large element fraction)

National Commendation for Invention
  The National Commendation for Invention, first issued in 1919 as the Imperial Commendation for Invention, has through the support of such organizations as the Ministry of Education, Culture, Sports, Science and Technology; the Ministry of Economy Trade and Industry, the Japan Patent Office; Nippon Keidanren (Japan Business Federation); the Japan Chamber of Commerce and Industry; and the Japan Patent Attorneys Association been awarded to inventors, people who have succeeded in the practical application of inventions, people who have rendered distinguished services in the working of inventions and people who have encouraged innovation. By fostering and encouraging invention, the award system is designed to contribute to the advancement of Japanese science and technology and the promotion of industry.
  The sponsoring organization, the Japan Institute of Invention and Innovation, has since its establishment in 1904 sought to contribute to the promotion and advancement of science and technology through activities that encourage invention and diffuse and develop the industrial property system.